Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study - Owen, David R; Guo, Qi; Kalk, Nicola J; Colasanti, Alessandro; Kalogiannopoulou, Dimitra; Dimber, Rahul; Lewis, Yvonne L; Libri, Vincenzo; Barletta, Julien; Ramada-Magalhaes, Joaquim; Kamalakaran, Aruloly; Nutt, David J; et al. (Journal of cerebral blood flow and metabolism, 2014)
Keywords: Acetamides - administration & dosage; Adult; Brain - diagnostic imaging; Brain - metabolism; Carbon Isotopes - administration & dosage; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Humans; Male; Original; Positron-Emission Tomography; Purines - administration & dosage; Pyridines - administration & dosage; Radiography; Receptors, GABA - metabolism; [11C]PBR28; TSPO; specific binding; rs6971 polymorphism; emapunil; XBD173