Effect of Dietetic Obesity on Testicular Transcriptome in Cynomolgus Monkeys

• Published in: Genes Vol. 14; no. 3; p. 557
• Main Authors: Zhang, Yanru, Qi, Jia, Zhao, Juan, Li, Miaojing, Zhang, Yulin, Hu, Huizhong, Wei, Liangliang, Zhou, Kai, Qin, Hongyu, Qu, Pengxiang, Cao, Wenbin, Liu, Enqi
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23.02.2023; MDPI
• Subjects: Alcohol; Animal Feed; Animals; blood; Body mass index; Cholesterol; Complications and side effects; diet; DNA methylation; Enzymes; Fertility; Gametes; Gene expression; Gene Expression Regulation; gene ontology; Genetic aspects; Health aspects; High cholesterol diet; High fat diet; humans; immunity; Infertility; inflammation; Interferon regulatory factor 1; Laboratory animals; Macaca fascicularis; male fertility; male sterility; males; metabolic diseases; Metabolic disorders; Metabolism; Monkeys & apes; Morphology; Obesity; Obesity - metabolism; Overweight; RNA; Sperm; Testes; Testis; Testis - metabolism; Testosterone; Testosterone - metabolism; Transcriptome; Transcriptomes; transcriptomics; China; United States > US; cynomolgus monkey; testis; transcriptome; obesity

Obesity is a metabolic disorder resulting from behavioral, environmental and heritable causes, and can have a negative impact on male reproduction. There have been few experiments in mice, rats, and rabbits on the effects of obesity on reproduction, which has inhibited the development of better trea...