Regulation of peroxisomal lipid metabolism: The role of acyl-CoA and coenzyme A metabolizing enzymes

• Published in: Biochimie Vol. 98; pp. 45 - 55
• Main Authors: Hunt, Mary C., Tillander, Veronika, Alexson, Stefan E.H.
• Format: Journal Article
• Language: English
• Published: France Elsevier B.V 01.03.2014
• Subjects: Acyl Coenzyme A - metabolism; Acyl-CoA thioesterase; Acyl-CoA:amino acid N-acyltransferase; Acyltransferases - metabolism; Animals; Biological Transport - physiology; Coenzyme A; Coenzyme A - metabolism; Coenzyme A-Transferases - metabolism; Fatty Acids - metabolism; Humans; Lipid Metabolism; Medicin och hälsovetenskap; Nudix hydrolase; Nudix Hydrolases; Peroxisomal lipid metabolism; Peroxisomes - metabolism; Pyrophosphatases - metabolism; Thiolester Hydrolases - metabolism; β-Oxidation; DMN-CoA; NAT; FAAH; AMP; Nudix hydrolase; β-Oxidation; FMN; PTS1; CoASH; CROT; ACNAT; BAAT; ADP; Acyl-CoA:amino acid N-acyltransferase; NUDT; PPAR; Acyl-CoA thioesterase; Coenzyme A; ACOT; Peroxisomal lipid metabolism; ACOX3; CRAT; PAP

Peroxisomes are nearly ubiquitous organelles involved in a number of metabolic pathways that vary between organisms and tissues. A common metabolic function in mammals is the partial degradation of various (di)carboxylic acids via α- and β-oxidation. While only a small number of enzymes catalyze the...