Granulomatous slack skin T-cell lymphoma: an important differential diagnosis with giant cell tumor of soft tissue

• Published in: Anais brasileiros de dermatología Vol. 90; no. 6; pp. 892 - 895
• Main Authors: Adriano, André Ricardo, Lima, Tiago Silveira, Battistella, Maxime, Bagot, Martine
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Sociedade Brasileira de Dermatologia 01.11.2015
• Subjects: Adult; Biopsy; Case Report; DERMATOLOGY; Diagnosis, Differential; Giant Cell Tumors - pathology; Humans; Immunohistochemistry; Lymphoma; Lymphoma, T-Cell, cutaneous; Lymphoma, T-Cell, Cutaneous - pathology; Male; Mycosis fungoides; Sarcoma; Skin Neoplasms - pathology; Soft tissue neoplasms; Soft Tissue Neoplasms - pathology; Mycosis fungoides; Lymphoma, T-Cell, cutaneous; Sarcoma; Soft tissue neoplasms; Lymphoma
• ISSN: 0365-0596; 1806-4841; 1806-4841; 0365-0596
• DOI: 10.1590/abd1806-4841.20153807

Granulomatous slack skin is an indolent T-cell lymphoma, considered to be a variant of mycosis fungoides. Clinically it is characterized by areas of redundant skin, wrinkled, inelastic, with variable erythema and infiltration besides a poikilodermic surface. A differential diagnosis unknown to most dermatologists is the giant cell tumor of soft tissue, which is an extremely rare low-grade sarcoma. The authors report a patient who had undergone extensive surgery because of a primary diagnosis of giant cell tumor of soft tissue, but which proved to be granulomatous slack skin after a second interventional procedure with confirmatory histopathology.