Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling

• Published in: International journal of molecular sciences Vol. 19; no. 10; p. 3220
• Main Authors: Schliermann, Anna, Nickel, Joachim
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 18.10.2018; MDPI AG
• Subjects: Animals; bone morphogenetic protein; Bone Morphogenetic Proteins - genetics; Bone Morphogenetic Proteins - metabolism; cross-talk; Disease Susceptibility; fibroblast growth factor; Fibroblast Growth Factors - genetics; Fibroblast Growth Factors - metabolism; Humans; Organ Specificity; Protein Binding; Review; signal integration; Signal Transduction; signal integration; fibroblast growth factor; cross-talk; signal transduction; bone morphogenetic protein

Ontogeny of higher organisms as well the regulation of tissue homeostasis in adult individuals requires a fine-balanced interplay of regulating factors that individually trigger the fate of particular cells to either stay undifferentiated or to differentiate towards distinct tissue specific lineages...