Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 289; no. 2; pp. H722 - H731
• Main Authors: Ascensao, Antonio, Magalhaes, Jose, Soares, Jose M. C, Ferreira, Rita, Neuparth, Maria J, Marques, Franklim, Oliveira, Paulo J, Duarte, Jose A
• Format: Journal Article
• Language: English
• Published: United States 01.08.2005
• Subjects: Animals; Apoptosis - drug effects; Cardiomyopathies - chemically induced; Cardiomyopathies - prevention & control; Doxorubicin - pharmacology; Heart - drug effects; Heart - physiology; Male; Mitochondria, Heart - drug effects; Mitochondria, Heart - metabolism; Mitochondria, Heart - physiology; Mitochondrial Diseases - chemically induced; Mitochondrial Diseases - prevention & control; Oxidative Stress; Oxygen Consumption - drug effects; Physical Conditioning, Animal; Physical Endurance; Rats; Rats, Wistar

1 Department of Sport Biology, Faculty of Sport Sciences, 2 Department of Biochemistry and Clinical Analysis, Faculty of Pharmacy, and 3 Institute for Molecular and Cell Biology, University of Porto, Porto; and 4 Centre of Neurosciences and Cell Biology, Department of Zoology, University of Coimbra,...