Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder

• Published in: Journal of child psychology and psychiatry Vol. 48; no. 12; pp. 1251 - 1258
• Main Authors: Brieber, Sarah, Neufang, Susanne, Bruning, Nicole, Kamp-Becker, Inge, Remschmidt, Helmut, Herpertz-Dahlmann, Beate, Fink, Gereon R., Konrad, Kerstin
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.12.2007; Blackwell Publishing; Blackwell
• Subjects: ADD/ADHD; Adolescent; Adolescents; Adult and adolescent clinical studies; Asperger Syndrome - diagnosis; Asperger Syndrome - pathology; Attention Deficit Disorder with Hyperactivity - diagnosis; Attention Deficit Disorder with Hyperactivity - pathology; Attention Deficit Disorders; Attention deficit disorders. Hyperactivity; Attention deficit hyperactivity disorder; Autism; autistic disorder; Autistic Disorder - diagnosis; Autistic Disorder - pathology; Autistic spectrum disorders; Biological and medical sciences; Brain; Brain - pathology; Brain Hemisphere Functions; Brain Mapping; Brain research; Child; Child clinical studies; Child psychology; Cognitive Processes; Comparative Analysis; Control Groups; Cortex; Developmental disorders; Diagnostic Tests; Frontal Lobe - pathology; Genetics; Humans; Hyperactivity; Identification; Image Processing, Computer-Assisted; Infantile autism; Interpersonal Relations; Magnetic Resonance Imaging; Medial temporal lobe; Medical sciences; Memory; Miscellaneous; Parietal Lobe - pathology; Patients; Pervasive Developmental Disorders; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Regional variations; Severity of Illness Index; structural MRI; Symptoms (Individual Disorders); Teenagers; Temporal Lobe - pathology; VBM; Human; VBM; structural MRI; Hyperactivity; autistic disorder; Central nervous system; Developmental disorder; Nuclear magnetic resonance imaging; Encephalon; Autism; Attentional disorder; Adolescent; Medical imagery; Attention disorder with hyperactivity; Morphometry; ADD/ADHD

Background:  Although autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are two distinct neurodevelopmental diseases, they share behavioural, neuropsychological and neurobiological characteristics. For the identification of endophenotypes across diagnostic categories...