Chinese expert consensus statement on the clinical application of AFP/AFP‐L3%/DCP using GALAD and GALAD‐like algorithm in HCC

• Published in: Journal of clinical laboratory analysis Vol. 37; no. 23-24; pp. e24990 - n/a
• Main Authors: Huang, Chenjun, Xiao, Xiao, Zhou, Lin, Chen, Fuxiang, Wang, Jianyi, Hu, Xiaobo, Gao, Chunfang, Chen, Jie, Duan, Yong, Duan, Zhaohui, Fang, Meng, Gao, Zhiyuan, Gu, Bing, Guo, Lin, Hu, Bo, Huang, Tao, Ji, Jun, Jia, Jianan, Jiang, Yanfang, Ju, Shaoqing, Ju, Yi, Lin, Jinbiao, Lin, Yong, Liu, Jiayun, Liu, Jie, Liu, Lijuan, Liu, Xinghui, Lou, Jiatao, Lou, Jinli, Lu, Qun, Lu, Renquan, Lu, Zhiming, Qiu, Zhiquan, Ren, Li, Sheng, Huiming, Su, Haixiang, Tao, Zhihua, Wang, Junjun, Wang, Ying, Wu, Wenjuan, Yang, Ximing, Yang, Zaixing, Yu, Zhuo, Yuan, Xiaopeng, Zhang, Rui, Zhang, Tao, Zhou, Qiang, Zhu, Junfeng, Zhu, Yuqing, Zhu, Zhaoqin
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.12.2023; John Wiley and Sons Inc
• Subjects: Algorithms; alpha‐fetoprotein (AFP); alpha‐fetoprotein‐L3% (AFP‐L3%); Biomarkers; Cancer therapies; Cholangiocarcinoma; Clinical medicine; Clinical practice guidelines; Consensus; des‐gamma‐carboxyprothrombin (DCP); Diagnosis; Family medical history; gender‐age‐AFP‐L3%‐AFP‐DCP (GALAD) model; Hepatitis B; Hepatocellular carcinoma; hepatocellular carcinoma (HCC); Liver cancer; Liver cirrhosis; Liver diseases; Malignancy; Medical diagnosis; Medical screening; Mortality; Surveillance; Tumors; Ultrasonic imaging; Viral infections; China; gender-age-AFP-L3%-AFP-DCP (GALAD) model; hepatocellular carcinoma (HCC); alpha-fetoprotein (AFP); des-gamma-carboxyprothrombin (DCP); alpha-fetoprotein-L3% (AFP-L3%)

Background Primary hepatocellular carcinoma (HCC) is one of the most prevalent world‐wide malignancies. Half of the newly developed HCC occurs in China. Optimizing the strategies for high‐risk surveillance and early diagnosis are pivotal for improving 5‐year survival. Constructing the scientific non...