A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 - Wu, Yan; Wang, Feiran; Shen, Chenguang; Peng, Weiyu; Li, Delin; Zhao, Cheng; Li, Zhaohui; Li, Shihua; Bi, Yuhai; Yang, Yang; Gong, Yuhuan; Xiao, Haixia; et al. (Science (American Association for the Advancement of Science), 2020)
Keywords: ACE2; Angiotensin; Angiotensin-Converting Enzyme 2; Animals; Antibodies; Antibodies, Monoclonal - immunology; Antibodies, Monoclonal - isolation & purification; Antibodies, Monoclonal - therapeutic use; Antibodies, Neutralizing - immunology; Antibodies, Neutralizing - isolation & purification; Antibodies, Neutralizing - therapeutic use; Antibodies, Viral - immunology; Antibodies, Viral - isolation & purification; Antibodies, Viral - therapeutic use; Antiviral agents; Antiviral drugs; Binding sites; Biochem; Blocking; Cellular structure; Coronaviridae; Coronavirus Infections - therapy; Coronaviruses; COVID-19; Disease Models, Animal; Domains; Enzymes; Epitopes; Glycoproteins; Humans; Immune system; Immunodominant Epitopes - chemistry; Immunodominant Epitopes - immunology; Lung - immunology; Lung - virology; Mice; Microbio; Monoclonal antibodies; Neutralization; Neutralization Tests; Neutralizing; Pandemics; Peptidyl-dipeptidase A; Peptidyl-Dipeptidase A - immunology; Pneumonia, Viral - therapy; Protein Domains; Receptors; Receptors, Virus - immunology; Spike glycoprotein; Spike Glycoprotein, Coronavirus - immunology; Spike protein; Therapeutic applications; Viral diseases; Viral Load - immunology; Viruses