Informative RNA base embedding for RNA structural alignment and clustering by deep representation learning

• Published in: NAR genomics and bioinformatics Vol. 4; no. 1; p. lqac012
• Main Authors: Akiyama, Manato, Sakakibara, Yasubumi
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.03.2022
• Subjects: Algorithms; Amino acid sequence; Deep learning; Embedding; Methods; Nucleotide sequence; Protein structure; Ribonucleic acid; RNA; Secondary structure

Abstract Effective embedding is actively conducted by applying deep learning to biomolecular information. Obtaining better embeddings enhances the quality of downstream analyses, such as DNA sequence motif detection and protein function prediction. In this study, we adopt a pre-training algorithm fo...