Association between Serum Selenium Level and the Presence of Diabetes Mellitus: A Meta-Analysis of Observational Studies
Epidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting results. Therefore, we performed a comprehensive meta-analysis to clarify the impact of Se on DM. We searched the PubMed database for studies o...
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| Published in | Diabetes & metabolism journal Vol. 43; no. 4; pp. 447 - 460 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
Korean Diabetes Association / Daehan Dangnyobyeong Hakoe
01.08.2019
Korean Diabetes Association 대한당뇨병학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 2233-6079 2233-6087 |
| DOI | 10.4093/dmj.2018.0123 |
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| Abstract | Epidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting results. Therefore, we performed a comprehensive meta-analysis to clarify the impact of Se on DM.
We searched the PubMed database for studies on the association between Se and DM from inception to June 2018.
Twenty articles evaluating 47,930 participants were included in the analysis. The meta-analysis found that high levels of Se were significantly associated with the presence of DM (pooled odds ratios [ORs], 1.88; 95% confidence interval [CI], 1.44 to 2.45). However, significant heterogeneity was found (
²=82%). Subgroup analyses were performed based on the Se measurement methods used in each study. A significant association was found between high Se levels and the presence of DM in the studies that used blood (OR, 2.17; 95% CI, 1.60 to 2.93;
²=77%), diet (OR, 1.61; 95% CI, 1.10 to 2.36;
²=0%), and urine (OR, 1.49; 95% CI, 1.02 to 2.17;
²=0%) as samples to estimate Se levels, but not in studies on nails (OR, 1.24; 95% CI, 0.52 to 2.98;
²=91%). Because of significant heterogeneity in the studies with blood, we conducted a sensitivity analysis and tested the publication bias. The results were consistent after adjustment based on the sensitivity analysis as well as the trim and fill analysis for publication bias.
This meta-analysis demonstrates that high levels of Se are associated with the presence of DM. Further prospective and randomized controlled trials are warranted to elucidate the link better. |
|---|---|
| AbstractList | Background Epidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting results. Therefore, we performed a comprehensive meta-analysis to clarify the impact of Se on DM.
Methods We searched the PubMed database for studies on the association between Se and DM from inception to June 2018.
Results Twenty articles evaluating 47,930 participants were included in the analysis. The meta-analysis found that high levels of Se were significantly associated with the presence of DM (pooled odds ratios [ORs], 1.88; 95% confidence interval [CI], 1.44 to 2.45). However, significant heterogeneity was found (I2=82%). Subgroup analyses were performed based on the Se measurement methods used in each study. A significant association was found between high Se levels and the presence of DM in the studies that used blood (OR, 2.17; 95% CI, 1.60 to 2.93; I2=77%), diet (OR, 1.61; 95% CI, 1.10 to 2.36; I2=0%), and urine (OR, 1.49; 95% CI, 1.02 to 2.17; I2=0%) as samples to estimate Se levels, but not in studies on nails (OR, 1.24; 95% CI, 0.52 to 2.98; I2=91%). Because of significant heterogeneity in the studies with blood, we conducted a sensitivity analysis and tested the publication bias. The results were consistent after adjustment based on the sensitivity analysis as well as the trim and fill analysis for publication bias.
Conclusion This meta-analysis demonstrates that high levels of Se are associated with the presence of DM. Further prospective and randomized controlled trials are warranted to elucidate the link better. KCI Citation Count: 35 Background Epidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting results. Therefore, we performed a comprehensive meta-analysis to clarify the impact of Se on DM.* Methods We searched the PubMed database for studies on the association between Se and DM from inception to June 2018.* Results Twenty articles evaluating 47,930 participants were included in the analysis. The meta-analysis found that high levels of Se were significantly associated with the presence of DM (pooled odds ratios [ORs], 1.88; 95% confidence interval [CI], 1.44 to 2.45). However, significant heterogeneity was found (I2=82%). Subgroup analyses were performed based on the Se measurement methods used in each study. A significant association was found between high Se levels and the presence of DM in the studies that used blood (OR, 2.17; 95% CI, 1.60 to 2.93; I2=77%), diet (OR, 1.61; 95% CI, 1.10 to 2.36; I2=0%), and urine (OR, 1.49; 95% CI, 1.02 to 2.17; I2=0%) as samples to estimate Se levels, but not in studies on nails (OR, 1.24; 95% CI, 0.52 to 2.98; I2=91%). Because of significant heterogeneity in the studies with blood, we conducted a sensitivity analysis and tested the publication bias. The results were consistent after adjustment based on the sensitivity analysis as well as the trim and fill analysis for publication bias.* Conclusion This meta-analysis demonstrates that high levels of Se are associated with the presence of DM. Further prospective and randomized controlled trials are warranted to elucidate the link better. Epidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting results. Therefore, we performed a comprehensive meta-analysis to clarify the impact of Se on DM.BACKGROUNDEpidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting results. Therefore, we performed a comprehensive meta-analysis to clarify the impact of Se on DM.We searched the PubMed database for studies on the association between Se and DM from inception to June 2018.METHODSWe searched the PubMed database for studies on the association between Se and DM from inception to June 2018.Twenty articles evaluating 47,930 participants were included in the analysis. The meta-analysis found that high levels of Se were significantly associated with the presence of DM (pooled odds ratios [ORs], 1.88; 95% confidence interval [CI], 1.44 to 2.45). However, significant heterogeneity was found (I²=82%). Subgroup analyses were performed based on the Se measurement methods used in each study. A significant association was found between high Se levels and the presence of DM in the studies that used blood (OR, 2.17; 95% CI, 1.60 to 2.93; I²=77%), diet (OR, 1.61; 95% CI, 1.10 to 2.36; I²=0%), and urine (OR, 1.49; 95% CI, 1.02 to 2.17; I²=0%) as samples to estimate Se levels, but not in studies on nails (OR, 1.24; 95% CI, 0.52 to 2.98; I²=91%). Because of significant heterogeneity in the studies with blood, we conducted a sensitivity analysis and tested the publication bias. The results were consistent after adjustment based on the sensitivity analysis as well as the trim and fill analysis for publication bias.RESULTSTwenty articles evaluating 47,930 participants were included in the analysis. The meta-analysis found that high levels of Se were significantly associated with the presence of DM (pooled odds ratios [ORs], 1.88; 95% confidence interval [CI], 1.44 to 2.45). However, significant heterogeneity was found (I²=82%). Subgroup analyses were performed based on the Se measurement methods used in each study. A significant association was found between high Se levels and the presence of DM in the studies that used blood (OR, 2.17; 95% CI, 1.60 to 2.93; I²=77%), diet (OR, 1.61; 95% CI, 1.10 to 2.36; I²=0%), and urine (OR, 1.49; 95% CI, 1.02 to 2.17; I²=0%) as samples to estimate Se levels, but not in studies on nails (OR, 1.24; 95% CI, 0.52 to 2.98; I²=91%). Because of significant heterogeneity in the studies with blood, we conducted a sensitivity analysis and tested the publication bias. The results were consistent after adjustment based on the sensitivity analysis as well as the trim and fill analysis for publication bias.This meta-analysis demonstrates that high levels of Se are associated with the presence of DM. Further prospective and randomized controlled trials are warranted to elucidate the link better.CONCLUSIONThis meta-analysis demonstrates that high levels of Se are associated with the presence of DM. Further prospective and randomized controlled trials are warranted to elucidate the link better. Epidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting results. Therefore, we performed a comprehensive meta-analysis to clarify the impact of Se on DM. We searched the PubMed database for studies on the association between Se and DM from inception to June 2018. Twenty articles evaluating 47,930 participants were included in the analysis. The meta-analysis found that high levels of Se were significantly associated with the presence of DM (pooled odds ratios [ORs], 1.88; 95% confidence interval [CI], 1.44 to 2.45). However, significant heterogeneity was found ( ²=82%). Subgroup analyses were performed based on the Se measurement methods used in each study. A significant association was found between high Se levels and the presence of DM in the studies that used blood (OR, 2.17; 95% CI, 1.60 to 2.93; ²=77%), diet (OR, 1.61; 95% CI, 1.10 to 2.36; ²=0%), and urine (OR, 1.49; 95% CI, 1.02 to 2.17; ²=0%) as samples to estimate Se levels, but not in studies on nails (OR, 1.24; 95% CI, 0.52 to 2.98; ²=91%). Because of significant heterogeneity in the studies with blood, we conducted a sensitivity analysis and tested the publication bias. The results were consistent after adjustment based on the sensitivity analysis as well as the trim and fill analysis for publication bias. This meta-analysis demonstrates that high levels of Se are associated with the presence of DM. Further prospective and randomized controlled trials are warranted to elucidate the link better. BackgroundEpidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting results. Therefore, we performed a comprehensive meta-analysis to clarify the impact of Se on DM.MethodsWe searched the PubMed database for studies on the association between Se and DM from inception to June 2018.ResultsTwenty articles evaluating 47,930 participants were included in the analysis. The meta-analysis found that high levels of Se were significantly associated with the presence of DM (pooled odds ratios [ORs], 1.88; 95% confidence interval [CI], 1.44 to 2.45). However, significant heterogeneity was found (I2=82%). Subgroup analyses were performed based on the Se measurement methods used in each study. A significant association was found between high Se levels and the presence of DM in the studies that used blood (OR, 2.17; 95% CI, 1.60 to 2.93; I2=77%), diet (OR, 1.61; 95% CI, 1.10 to 2.36; I2=0%), and urine (OR, 1.49; 95% CI, 1.02 to 2.17; I2=0%) as samples to estimate Se levels, but not in studies on nails (OR, 1.24; 95% CI, 0.52 to 2.98; I2=91%). Because of significant heterogeneity in the studies with blood, we conducted a sensitivity analysis and tested the publication bias. The results were consistent after adjustment based on the sensitivity analysis as well as the trim and fill analysis for publication bias.ConclusionThis meta-analysis demonstrates that high levels of Se are associated with the presence of DM. Further prospective and randomized controlled trials are warranted to elucidate the link better. |
| Author | Chung, Hye Soo Park, Jung Hwan Kim, Dong Sun Kim, Juno Yoo, Hyung Joon Moon, Shinje Yu, Jae Myung Choi, Min-Kyu Roh, Yong Kyun |
| AuthorAffiliation | 5 Department of Internal Medicine, Graduate School, Hanyang University College of Medicine, Seoul, Korea 3 Division of Internal Medicine, CM Hospital, Seoul, Korea 4 Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea 1 Department of Family Medicine, Hallym University College of Medicine, Chuncheon, Korea |
| AuthorAffiliation_xml | – name: 4 Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea – name: 1 Department of Family Medicine, Hallym University College of Medicine, Chuncheon, Korea – name: 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea – name: 5 Department of Internal Medicine, Graduate School, Hanyang University College of Medicine, Seoul, Korea – name: 3 Division of Internal Medicine, CM Hospital, Seoul, Korea |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30688047$$D View this record in MEDLINE/PubMed https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002493927$$DAccess content in National Research Foundation of Korea (NRF) |
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| Cites_doi | 10.1016/S0753-3322(03)00035-0 10.1186/s12937-015-0007-2 10.1016/j.jinorgbio.2012.04.011 10.1016/j.jnutbio.2005.10.006 10.1136/bmjdrc-2016-000253 10.1371/journal.pone.0123742 10.1186/s12937-016-0169-6 10.1002/hep.24808 10.1016/j.atherosclerosis.2011.03.027 10.3390/nu8020080 10.1016/S0140-6736(11)61452-9 10.1093/jn/nxy099 10.1038/nature04634 10.2337/diab.40.12.1675 10.1016/j.jnutbio.2008.02.007 10.1016/j.envpol.2015.11.046 10.1007/s12011-016-0868-z 10.1016/j.envpol.2018.01.046 10.3945/jn.112.159020 10.1007/BF00400407 10.1016/j.redox.2017.04.022 10.1016/j.freeradbiomed.2012.01.017 10.1007/PL00000669 10.1177/174182679600300106 10.1016/j.bbagen.2009.02.014 10.1016/j.jtemb.2014.07.017 10.1001/jama.2008.864 10.1111/dme.12429 10.1007/s12020-014-0298-7 10.2337/dc06-1726 10.1016/j.freeradbiomed.2013.07.012 10.7326/0003-4819-147-4-200708210-00175 10.1016/S0024-3205(96)00550-4 10.1073/pnas.0308096101 10.1289/ehp.0900704 10.1038/ejcn.2015.92 10.1016/j.jtemb.2016.12.017 10.3390/molecules18033292 10.2337/dc11-2136 10.1016/j.jtemb.2016.12.008 10.1016/0378-4274(91)90174-5 10.1186/1471-2458-10-564 10.1023/A:1006819906820 10.1016/S0021-9258(19)40166-X 10.1002/jbt.10058 |
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| Copyright | Copyright © 2019 Korean Diabetes Association. 2019. This work is licensed under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © 2019 Korean Diabetes Association 2019 Korean Diabetes Association |
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| Keywords | Antioxidants Trace elements Selenium Diabetes mellitus |
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| References | Lippman (10.4093/dmj.2018.0123_ref48) 2009; 301 McClung (10.4093/dmj.2018.0123_ref46) 2004; 101 Skalnaya (10.4093/dmj.2018.0123_ref28) 2017; 177 Stranges (10.4093/dmj.2018.0123_ref31) 2011; 217 Li (10.4093/dmj.2018.0123_ref19) 2017; 30 Liu (10.4093/dmj.2018.0123_ref35) 2016; 210 Maritim (10.4093/dmj.2018.0123_ref11) 2003; 17 Ezaki (10.4093/dmj.2018.0123_ref12) 1990; 265 Hei (10.4093/dmj.2018.0123_ref13) 1998; 178 Galan-Chilet (10.4093/dmj.2018.0123_ref25) 2017; 12 Mueller (10.4093/dmj.2018.0123_ref41) 2009; 20 Rayman (10.4093/dmj.2018.0123_ref5) 2012; 379 Zeng (10.4093/dmj.2018.0123_ref42) 2012; 52 Wei (10.4093/dmj.2018.0123_ref37) 2015; 14 Pinto (10.4093/dmj.2018.0123_ref44) 2012; 114 Mao (10.4093/dmj.2018.0123_ref8) 2014; 47 Mehdi (10.4093/dmj.2018.0123_ref1) 2013; 18 Zhou (10.4093/dmj.2018.0123_ref45) 2013; 65 Houstis (10.4093/dmj.2018.0123_ref10) 2006; 440 Stranges (10.4093/dmj.2018.0123_ref38) 2010; 10 McNeill (10.4093/dmj.2018.0123_ref16) 1991; 40 Becker (10.4093/dmj.2018.0123_ref17) 1996; 39 Kohler (10.4093/dmj.2018.0123_ref18) 2018; 148 Laclaustra (10.4093/dmj.2018.0123_ref20) 2009; 117 Mueller (10.4093/dmj.2018.0123_ref15) 2006; 17 Rasekh (10.4093/dmj.2018.0123_ref40) 1991; 58 Liu (10.4093/dmj.2018.0123_ref43) 2012; 142 Rostom (10.4093/dmj.2018.0123_ref26) 2004; 104 Wang (10.4093/dmj.2018.0123_ref7) 2016; 15 Park (10.4093/dmj.2018.0123_ref21) 2012; 35 Rohr-Udilova (10.4093/dmj.2018.0123_ref3) 2012; 55 Steinbrenner (10.4093/dmj.2018.0123_ref6) 2009; 1790 Yuan (10.4093/dmj.2018.0123_ref24) 2018; 237 Ogawa-Wong (10.4093/dmj.2018.0123_ref9) 2016; 8 Thompson (10.4093/dmj.2018.0123_ref49) 2016; 108 Gao (10.4093/dmj.2018.0123_ref23) 2014; 31 Furnsinn (10.4093/dmj.2018.0123_ref14) 1996; 59 Bleys (10.4093/dmj.2018.0123_ref32) 2007; 30 Vinceti (10.4093/dmj.2018.0123_ref34) 2015; 29 Hansen (10.4093/dmj.2018.0123_ref22) 2017; 40 Nève (10.4093/dmj.2018.0123_ref4) 1996; 3 Feng (10.4093/dmj.2018.0123_ref36) 2015; 10 Su (10.4093/dmj.2018.0123_ref33) 2016; 29 Lu (10.4093/dmj.2018.0123_ref29) 2016; 4 Alehagen (10.4093/dmj.2018.0123_ref30) 2016; 70 Stranges (10.4093/dmj.2018.0123_ref47) 2007; 147 Tapiero (10.4093/dmj.2018.0123_ref2) 2003; 57 Zhang (10.4093/dmj.2018.0123_ref27) 2017; 40 Stapleton (10.4093/dmj.2018.0123_ref39) 2000; 57 |
| References_xml | – volume: 57 start-page: 134 year: 2003 ident: 10.4093/dmj.2018.0123_ref2 publication-title: Biomed Pharmacother doi: 10.1016/S0753-3322(03)00035-0 – volume: 14 start-page: 18 year: 2015 ident: 10.4093/dmj.2018.0123_ref37 publication-title: Nutr J doi: 10.1186/s12937-015-0007-2 – volume: 114 start-page: 47 year: 2012 ident: 10.4093/dmj.2018.0123_ref44 publication-title: J Inorg Biochem doi: 10.1016/j.jinorgbio.2012.04.011 – volume: 17 start-page: 548 year: 2006 ident: 10.4093/dmj.2018.0123_ref15 publication-title: J Nutr Biochem doi: 10.1016/j.jnutbio.2005.10.006 – volume: 4 start-page: e000253 year: 2016 ident: 10.4093/dmj.2018.0123_ref29 publication-title: BMJ Open Diabetes Res Care doi: 10.1136/bmjdrc-2016-000253 – volume: 10 start-page: e0123742 year: 2015 ident: 10.4093/dmj.2018.0123_ref36 publication-title: PLoS One doi: 10.1371/journal.pone.0123742 – volume: 15 start-page: 48 year: 2016 ident: 10.4093/dmj.2018.0123_ref7 publication-title: Nutr J doi: 10.1186/s12937-016-0169-6 – volume: 30 start-page: 482 year: 2017 ident: 10.4093/dmj.2018.0123_ref19 publication-title: Biomed Environ Sci – volume: 55 start-page: 1112 year: 2012 ident: 10.4093/dmj.2018.0123_ref3 publication-title: Hepatology doi: 10.1002/hep.24808 – volume: 217 start-page: 274 year: 2011 ident: 10.4093/dmj.2018.0123_ref31 publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2011.03.027 – volume: 8 start-page: 80 year: 2016 ident: 10.4093/dmj.2018.0123_ref9 publication-title: Nutrients doi: 10.3390/nu8020080 – volume: 104 start-page: 1 year: 2004 ident: 10.4093/dmj.2018.0123_ref26 publication-title: Evid Rep Technol Assess (Summ) – volume: 379 start-page: 1256 year: 2012 ident: 10.4093/dmj.2018.0123_ref5 publication-title: Lancet doi: 10.1016/S0140-6736(11)61452-9 – volume: 148 start-page: 1333 year: 2018 ident: 10.4093/dmj.2018.0123_ref18 publication-title: J Nutr doi: 10.1093/jn/nxy099 – volume: 440 start-page: 944 year: 2006 ident: 10.4093/dmj.2018.0123_ref10 publication-title: Nature doi: 10.1038/nature04634 – volume: 40 start-page: 1675 year: 1991 ident: 10.4093/dmj.2018.0123_ref16 publication-title: Diabetes doi: 10.2337/diab.40.12.1675 – volume: 20 start-page: 235 year: 2009 ident: 10.4093/dmj.2018.0123_ref41 publication-title: J Nutr Biochem doi: 10.1016/j.jnutbio.2008.02.007 – volume: 210 start-page: 1 year: 2016 ident: 10.4093/dmj.2018.0123_ref35 publication-title: Environ Pollut doi: 10.1016/j.envpol.2015.11.046 – volume: 177 start-page: 25 year: 2017 ident: 10.4093/dmj.2018.0123_ref28 publication-title: Biol Trace Elem Res doi: 10.1007/s12011-016-0868-z – volume: 237 start-page: 917 year: 2018 ident: 10.4093/dmj.2018.0123_ref24 publication-title: Environ Pollut doi: 10.1016/j.envpol.2018.01.046 – volume: 142 start-page: 1410 year: 2012 ident: 10.4093/dmj.2018.0123_ref43 publication-title: J Nutr doi: 10.3945/jn.112.159020 – volume: 39 start-page: 3 year: 1996 ident: 10.4093/dmj.2018.0123_ref17 publication-title: Diabetologia doi: 10.1007/BF00400407 – volume: 12 start-page: 798 year: 2017 ident: 10.4093/dmj.2018.0123_ref25 publication-title: Redox Biol doi: 10.1016/j.redox.2017.04.022 – volume: 52 start-page: 1335 year: 2012 ident: 10.4093/dmj.2018.0123_ref42 publication-title: Free Radic Biol Med doi: 10.1016/j.freeradbiomed.2012.01.017 – volume: 57 start-page: 1874 year: 2000 ident: 10.4093/dmj.2018.0123_ref39 publication-title: Cell Mol Life Sci doi: 10.1007/PL00000669 – volume: 3 start-page: 42 year: 1996 ident: 10.4093/dmj.2018.0123_ref4 publication-title: J Cardiovasc Risk doi: 10.1177/174182679600300106 – volume: 1790 start-page: 1478 year: 2009 ident: 10.4093/dmj.2018.0123_ref6 publication-title: Biochim Biophys Acta doi: 10.1016/j.bbagen.2009.02.014 – volume: 29 start-page: 145 year: 2015 ident: 10.4093/dmj.2018.0123_ref34 publication-title: J Trace Elem Med Biol doi: 10.1016/j.jtemb.2014.07.017 – volume: 301 start-page: 39 year: 2009 ident: 10.4093/dmj.2018.0123_ref48 publication-title: JAMA doi: 10.1001/jama.2008.864 – volume: 31 start-page: 787 year: 2014 ident: 10.4093/dmj.2018.0123_ref23 publication-title: Diabet Med doi: 10.1111/dme.12429 – volume: 47 start-page: 758 year: 2014 ident: 10.4093/dmj.2018.0123_ref8 publication-title: Endocrine doi: 10.1007/s12020-014-0298-7 – volume: 30 start-page: 829 year: 2007 ident: 10.4093/dmj.2018.0123_ref32 publication-title: Diabetes Care doi: 10.2337/dc06-1726 – volume: 65 start-page: 1548 year: 2013 ident: 10.4093/dmj.2018.0123_ref45 publication-title: Free Radic Biol Med doi: 10.1016/j.freeradbiomed.2013.07.012 – volume: 147 start-page: 217 year: 2007 ident: 10.4093/dmj.2018.0123_ref47 publication-title: Ann Intern Med doi: 10.7326/0003-4819-147-4-200708210-00175 – volume: 59 start-page: 1989 year: 1996 ident: 10.4093/dmj.2018.0123_ref14 publication-title: Life Sci doi: 10.1016/S0024-3205(96)00550-4 – volume: 101 start-page: 8852 year: 2004 ident: 10.4093/dmj.2018.0123_ref46 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0308096101 – volume: 117 start-page: 1409 year: 2009 ident: 10.4093/dmj.2018.0123_ref20 publication-title: Environ Health Perspect doi: 10.1289/ehp.0900704 – volume: 70 start-page: 91 year: 2016 ident: 10.4093/dmj.2018.0123_ref30 publication-title: Eur J Clin Nutr doi: 10.1038/ejcn.2015.92 – volume: 40 start-page: 91 year: 2017 ident: 10.4093/dmj.2018.0123_ref27 publication-title: J Trace Elem Med Biol doi: 10.1016/j.jtemb.2016.12.017 – volume: 18 start-page: 3292 year: 2013 ident: 10.4093/dmj.2018.0123_ref1 publication-title: Molecules doi: 10.3390/molecules18033292 – volume: 35 start-page: 1544 year: 2012 ident: 10.4093/dmj.2018.0123_ref21 publication-title: Diabetes Care doi: 10.2337/dc11-2136 – volume: 108 start-page: djw152 year: 2016 ident: 10.4093/dmj.2018.0123_ref49 publication-title: J Natl Cancer Inst – volume: 40 start-page: 46 year: 2017 ident: 10.4093/dmj.2018.0123_ref22 publication-title: J Trace Elem Med Biol doi: 10.1016/j.jtemb.2016.12.008 – volume: 58 start-page: 199 year: 1991 ident: 10.4093/dmj.2018.0123_ref40 publication-title: Toxicol Lett doi: 10.1016/0378-4274(91)90174-5 – volume: 29 start-page: 818 year: 2016 ident: 10.4093/dmj.2018.0123_ref33 publication-title: Biomed Environ Sci – volume: 10 start-page: 564 year: 2010 ident: 10.4093/dmj.2018.0123_ref38 publication-title: BMC Public Health doi: 10.1186/1471-2458-10-564 – volume: 178 start-page: 367 year: 1998 ident: 10.4093/dmj.2018.0123_ref13 publication-title: Mol Cell Biochem doi: 10.1023/A:1006819906820 – volume: 265 start-page: 1124 year: 1990 ident: 10.4093/dmj.2018.0123_ref12 publication-title: J Biol Chem doi: 10.1016/S0021-9258(19)40166-X – volume: 17 start-page: 24 year: 2003 ident: 10.4093/dmj.2018.0123_ref11 publication-title: J Biochem Mol Toxicol doi: 10.1002/jbt.10058 |
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| Snippet | Epidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported conflicting... Background Epidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported... BackgroundEpidemiological studies have suggested an association between selenium (Se) and diabetes mellitus (DM). However, different studies have reported... |
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| SubjectTerms | Adult Aged antioxidants Bias Databases, Factual Diabetes diabetes mellitus Diabetes Mellitus - blood Diabetes Mellitus - epidemiology Diabetes Mellitus - urine Female Humans Insulin resistance Investigations Kinases Male Meta-analysis Middle Aged Nails - chemistry Observational studies Observational Studies as Topic Odds Ratio Original Oxidative stress Publication Bias Selenium Selenium - blood Selenium - urine Sensitivity analysis trace elements 내과학 |
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| Title | Association between Serum Selenium Level and the Presence of Diabetes Mellitus: A Meta-Analysis of Observational Studies |
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