Effects of treatment with corticosteroids on human rhinovirus-induced asthma exacerbations in pediatric inpatients: a prospective observational study

• Published in: BMC pulmonary medicine Vol. 23; no. 1; pp. 487 - 8
• Main Authors: Kan-o, Keiko, Washio, Yasuyoshi, Oki, Takeshi, Fujimoto, Tsuguto, Ninomiya, Takahito, Yoshida, Makoto, Fujita, Masaki, Nakanishi, Yoichi, Matsumoto, Koichiro
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.12.2023; BioMed Central; BMC
• Subjects: Administration, Inhalation; Adrenal Cortex Hormones; Analysis; Anti-Asthmatic Agents - therapeutic use; Asthma; Asthma - chemically induced; Asthma - drug therapy; Asthma in children; Child; Children; Clinical outcomes; Corticosteroids; Exacerbation; Health aspects; Hospital patients; Hospitals; Human rhinovirus; Humans; Infection; Infections; Influenza; Inpatients; Laboratories; Medical research; Medicine, Experimental; Observational studies; Pathogens; Patients; Pediatric asthma; Pediatrics; Pulmonary function tests; Pulmonology; Respiratory function; Respiratory syncytial virus; Rhinovirus; Steroids; Viral infections; Viruses; Japan; United States > US; Exacerbation; Pediatric asthma; Corticosteroids; Human rhinovirus

Human rhinoviruses (HRVs) infection is a common cause of exacerbations in pediatric patients with asthma. However, the effects of corticosteroids on HRV-induced exacerbations in pediatric asthma are unknown. We conducted a prospective observational study to determine the viral pathogens in school-ag...