Salivary leptin and TAS1R2/TAS1R3 polymorphisms are related to sweet taste sensitivity and carbohydrate intake from a buffet meal in healthy young adults

• Published in: British journal of nutrition Vol. 118; no. 10; pp. 763 - 770
• Main Authors: Han, Pengfei, Keast, Russell S. J., Roura, Eugeni
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 28.11.2017
• Subjects: Adult; Adults; Alleles; Appetite; Appetite Regulation - genetics; carbohydrate intake; Carbohydrates; cross-over studies; Dietary Carbohydrates - administration & dosage; dietary energy sources; Eating; Energy; Energy consumption; Energy Intake; Female; Food; Food consumption; Food intake; Food Preferences - physiology; Genotype; Humans; Hunger; Laboratories; Leptin; Leptin - metabolism; lipid content; loci; luteinizing hormone; Male; Meals; Molecular Nutrition; Mouth Mucosa; Nutrition; Obesity; Otolaryngology; Polymorphism, Single Nucleotide; Preferences; Receptors, G-Protein-Coupled - genetics; Rodents; Saliva; Saliva - metabolism; Satiation; Satiety; Satiety Response; Sensitivity; Single-nucleotide polymorphism; soups; Sucrose; Sugar; Sweet taste; Sweetness; Taste; Taste Buds; Taste Perception - genetics; Taste receptors; taste sensitivity; Taste thresholds; Young adults; Salivary leptin; Sweet sensitivity; Food intake; Sensory-specific satiety; TAS1R2/TAS1R3 polymorphisms; HS high sweet sensitive; LS low sweet sensitive; SSS sensory-specific satiety

The influence of sweet taste sensitivity on food intake is not well understood. We investigated the involvement of salivary leptin and SNP of the sweet taste receptor genes (TAS1R2/TAS1R3) on sweet taste sensitivity, sensory-specific satiety (SSS) and macronutrient intake in healthy human adults. In...