Estimating infectiousness throughout SARS-CoV-2 infection course

• Published in: Science (American Association for the Advancement of Science) Vol. 373; no. 6551
• Main Authors: Jones, Terry C., Biele, Guido, Mühlemann, Barbara, Veith, Talitha, Schneider, Julia, Beheim-Schwarzbach, Jörn, Bleicker, Tobias, Tesch, Julia, Schmidt, Marie Luisa, Sander, Leif Erik, Kurth, Florian, Menzel, Peter, Schwarzer, Rolf, Zuchowski, Marta, Hofmann, Jörg, Krumbholz, Andi, Stein, Angela, Edelmann, Anke, Corman, Victor Max, Drosten, Christian
• Format: Journal Article
• Language: English
• Published: United States The American Association for the Advancement of Science 09.07.2021; American Association for the Advancement of Science
• Subjects: Adolescent; Adult; Adults; Age; Age Factors; Aged; Aged, 80 and over; Asymptomatic; Asymptomatic Infections; Caco-2 Cells; Cell culture; Child; Child, Preschool; Children; Clinical significance; Containment; Coronaviruses; COVID-19; COVID-19 - diagnosis; COVID-19 - transmission; COVID-19 - virology; COVID-19 Nucleic Acid Testing; Disease transmission; Estimates; Female; Germany; Hospitalization; Humans; Infant; Infections; Infectivity; Load distribution; Male; Mean; Middle Aged; Online; Parameters; Patients; Peak load; Probability; Replication; Respiratory diseases; SARS-CoV-2 - isolation & purification; SARS-CoV-2 - pathogenicity; SARS-CoV-2 - physiology; Severe acute respiratory syndrome coronavirus 2; Viral diseases; Viral infections; Viral Load; Virology; Virus Replication; Virus Shedding; Viruses; Young Adult; Germany

The role that individuals with asymptomatic or mildly symptomatic severe acute respiratory syndrome coronavirus 2 have in transmission of the virus is not well understood. Jones et al. investigated viral load in patients, comparing those showing few, if any, symptoms with hospitalized cases. Approxi...