A Preclinical Animal Model to Assess the Effect of Pre-existing Immunity on AAV-mediated Gene Transfer - Li, Hua; Lin, Shih-Wen; Giles-Davis, Wynetta; Li, Yan; Zhou, Dongming; Xiang, Zhi Quan; High, Katherine A; Ertl, Hildegund CJ (Molecular therapy, 2009)
Keywords: Adenoviridae - genetics; Adenoviridae - immunology; Adenoviruses; Animals; Antibodies; Antigens; B-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - immunology; Cell Line; Cytokines; Enzyme-Linked Immunosorbent Assay; Gene therapy; Gene Transfer Techniques; Genetic Vectors - genetics; Genetic Vectors - immunology; Genomes; Human subjects; Humans; Interferon; Killer Cells, Natural - immunology; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Models, Animal; Original; Polymerase Chain Reaction; Tumor necrosis factor-TNF; Vectors (Biology); United States--US; Pennsylvania