High-Risk Neuroblastoma Stage 4 (NBS4): Developing a Medicinal Chemistry Multi-Target Drug Approach - Gerges, Amgad; Canning, Una (Molecules (Basel, Switzerland), 2025)
Keywords: Amino acids; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Cancer therapies; Cell cycle; Cell Cycle Proteins - antagonists & inhibitors; Cell Cycle Proteins - chemistry; Cell Cycle Proteins - metabolism; Chemistry, Pharmaceutical; Child; compounds; cross-docking; docking; Epigenetics; Gene amplification; Hedgehog Proteins - antagonists & inhibitors; Hedgehog Proteins - chemistry; Hedgehog Proteins - metabolism; Histone Deacetylase Inhibitors - chemistry; Histone Deacetylase Inhibitors - pharmacology; Humans; Kinases; Molecular Docking Simulation; multi-target drugs; Neoplasm Staging; Neuroblastoma; Neuroblastoma - drug therapy; Neuroblastoma - metabolism; Neuroblastoma - pathology; neuroblastoma stage 4 (NBS4); Pharmaceutical sciences; Proteins; Quantitative Structure-Activity Relationship; receptors; Vismodegib; New Brunswick; docking; neuroblastoma stage 4 (NBS4); receptors; compounds; multi-target drugs; cross-docking; binding interaction