Human pharmacology of intravenous lisdexamfetamine dimesylate: abuse liability in adult stimulant abusers

• Published in: Journal of psychopharmacology (Oxford) Vol. 23; no. 4; p. 410
• Main Authors: Jasinski, D R, Krishnan, S
• Format: Journal Article
• Language: English
• Published: United States 01.06.2009
• Subjects: Central Nervous System Stimulants - adverse effects; Dextroamphetamine - administration & dosage; Dextroamphetamine - adverse effects; Dextroamphetamine - pharmacokinetics; Dextroamphetamine - pharmacology; Double-Blind Method; Humans; Injections, Intravenous; Lisdexamfetamine Dimesylate; Male; Middle Aged; Prodrugs - administration & dosage; Prodrugs - adverse effects; Prodrugs - pharmacokinetics; Prodrugs - pharmacology; Substance-Related Disorders - prevention & control
• ISSN: 0269-8811
• DOI: 10.1177/0269881108093841

The objective of this study is to determine the safety, tolerability and abuse liability of single intravenous (i.v.) doses of lisdexamfetamine dimesylate (LDX) and immediate-release d-amphetamine sulphate in adult stimulant abusers compared with placebo. Adult substance abusers were enrolled in thi...