Self-Nanoemulsifying Drug Delivery System-Containing the Poorly Absorbed Drug – Valsartan in Post-Bariatric Surgery

• Published in: International journal of nanomedicine Vol. 18; pp. 2647 - 2658
• Main Authors: Huang, Tzu-Hao, Chen, Chih-Jung, Lin, Hsin-Chia Angela, Chen, Chun-Han, Fang, Jia-You
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01.01.2023; Dove; Dove Medical Press
• Subjects: Animals; Bariatric Surgery; Body weight; Caco-2 Cells; Cardiovascular agents; Drug Delivery Systems; Drugs; gastric bypass; Health aspects; High performance liquid chromatography; Humans; Hypertension; nano drug-delivery system; Obesity; Original Research; Pharmaceutical Preparations; sleeve gastrectomy; Surgery; Valsartan; Vehicles; Taiwan; valsartan; nano-drug delivery system; sleeve gastrectomy; gastric bypass

Morbid obesity and its related metabolic syndrome are an important health issue. Recently, sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) have accounted for the most popular bariatric surgeries. Valsartan (VST) is a common hypertension drug, and nano-carriers can increase its solubility...