Chelerythrine Chloride Alleviated Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting Glycolytic Pathway Through Targeting Glyceraldehyde-3-Phosphate Dehydrogenase - He, Yuting; Fan, Tianyun; Zhuge, Ruishen; Li, Huiying; Li, Guanjun; Zhou, Lirun; Xu, Liting; Hao, Xiaojiang; Gu, Wei; Wang, Jigang (Molecules (Basel, Switzerland), 2025)
Keywords: acute lung injury; Acute Lung Injury - chemically induced; Acute Lung Injury - drug therapy; Acute Lung Injury - metabolism; Acute Lung Injury - pathology; Animals; Anti-Inflammatory Agents - pharmacology; Benzophenanthridines - pharmacology; chelerythrine chloride; Chelidonium majus L; Cytokines; Dehydrogenases; Disease Models, Animal; Edema; Enzymes; Glucose metabolism; glyceraldehyde-3-phosphate dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism; glycolysis; Glycolysis - drug effects; Health aspects; Inflammation; Inflammatory diseases; Interleukins; Investigations; Labeling; Lipopolysaccharides - adverse effects; Lung diseases; Male; Metabolism; Metabolites; Mice; Monosaccharides; Nitric oxide; Nitric Oxide - metabolism; Phosphates; Proteins; RAW 264.7 Cells; Sugars; Toxicity; Tumor necrosis factor; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-TNF; China; chelerythrine chloride; Chelidonium majus L; glyceraldehyde-3-phosphate dehydrogenase; acute lung injury; glycolysis