Putative Neuroprotective and Neurotoxic Kynurenine Pathway Metabolites Are Associated with Hippocampal and Amygdalar Volumes in Subjects with Major Depressive Disorder - Savitz, Jonathan; Drevets, Wayne C; Smith, Chelsey M; Victor, Teresa A; Wurfel, Brent E; Bellgowan, Patrick SF; Bodurka, Jerzy; Teague, T Kent; Dantzer, Robert (Neuropsychopharmacology (New York, N.Y.), 2015)
Keywords: Acids; Adult; Amygdala - pathology; Anhedonia; Atrophy; Brain research; Brain-Derived Neurotrophic Factor - blood; C-Reactive Protein - metabolism; Comorbidity; Cytokines; Depressive Disorder, Major - blood; Depressive Disorder, Major - pathology; Enzymes; Female; Gray Matter - pathology; Hippocampus - pathology; Humans; Inflammation; Kynurenic Acid - blood; Kynurenine - analogs & derivatives; Kynurenine - blood; Male; Mental depression; Metabolites; Neurogenesis; Neurotoxicity; Organ Size; Original; Psychiatric Status Rating Scales; Quinolinic Acid - blood; Receptors, Interleukin-1 - blood; Signal Transduction; Tryptophan - blood; Tumor necrosis factor-TNF; United States--US