Long-Term Tolerability and Effectiveness of Once-Daily Mixed Amphetamine Salts (Adderall XR) in Children with ADHD

• Published in: Journal of the American Academy of Child and Adolescent Psychiatry Vol. 44; no. 6; pp. 530 - 538
• Main Authors: McGough, James J, Biederman, Joseph, Wigal, Sharon B, Lopez, Frank A, McCracken, James T, Spencer, Thomas, Zhang, Yuxin, Tulloch, Simon J
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 01.06.2005
• Subjects: Amphetamines - administration & dosage; Amphetamines - adverse effects; Attention Deficit Disorder with Hyperactivity - diagnosis; Attention Deficit Disorder with Hyperactivity - drug therapy; Attention Deficit Disorders; Attention Span; Behavior Change; Central Nervous System Stimulants - administration & dosage; Central Nervous System Stimulants - adverse effects; Child; Children; Delayed-Action Preparations; Drug Administration Schedule; Drug Therapy; Female; Follow-Up Studies; Humans; Hyperactivity; Long-Term Care; Male; Personality Assessment; Symptoms (Individual Disorders); Treatment Outcome

Objective: To evaluate the long-term tolerability and effectiveness of extended-release mixed amphetamine salts (MAS XR; Adderall XR[R]) in children with attention-deficit/hyperactivity disorder (ADHD). Method: This was a 24-month, multicenter, open-label extension of TWO placebo-controlled studies...