Progression from cardiomyopathy to heart failure with reduced ejection fraction: A CORIN deficient course

• Published in: Heliyon Vol. 10; no. 18; p. e37838
• Main Authors: Kan, Jun-yan, Wang, Dong-chen, Jiang, Zi-hao, Wu, Li-da, Xu, Ke, Gu, Yue
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 30.09.2024; Elsevier
• Subjects: algorithms; Bioinformatics; biomarkers; Cardiomyopathy; CORIN; fibroblasts; fibrosis; heart failure; Heart failure with reduced ejection fraction; microarray technology; Molecular subtypes; myocardium; patients; prognosis; rats; RNA; sequence analysis; therapeutics; Molecular subtypes; Heart failure with reduced ejection fraction; Cardiomyopathy; Bioinformatics; CORIN

Cardiomyopathies, encompassing hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM), constitute a diverse spectrum of heart muscle diseases that often culminating in heart failure (HF). The inherent molecular heterogeneity of these conditions has implications for prognosis and therapeu...