Targeting of severe fever with thrombocytopenia syndrome virus structural proteins to the ERGIC (endoplasmic reticulum Golgi intermediate compartment) and Golgi complex

• Published in: Biomedical Research Vol. 39; no. 1; pp. 27 - 38
• Main Authors: LUNDU, Tapiwa, TSUDA, Yoshimi, ITO, Ryo, SHIMIZU, Kenta, KOBAYASHI, Shintaro, YOSHII, Kentaro, YOSHIMATSU, Kumiko, ARIKAWA, Jiro, KARIWA, Hiroaki
• Format: Journal Article
• Language: English
• Published: Japan Biomedical Research Press 01.01.2018; Japan Science and Technology Agency
• Subjects: Compartments; Confocal microscopy; DNA-directed RNA polymerase; Endoplasmic reticulum; Fever; Glycoproteins; Golgi apparatus; Hemagglutinins; Localization; Microscopy; Nucleocapsids; Proteins; RNA polymerase; RNA-directed RNA polymerase; Structural proteins; Thrombocytopenia; Viruses

Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) is a newly emerged phlebovirus identified in China, Japan, and South Korea. Phlebovirus glycoproteins (GP) play a key role in targeting viral structural components to the budding compartments in the ER–Golgi intermediate compartment (ER...