STOP knockout and NMDA NR1 hypomorphic mice exhibit deficits in sensorimotor gating - Fradley, Rosa L.; O’Meara, Gillian F.; Newman, Richard J.; Andrieux, Annie; Job, Didier; Reynolds, David S. (Behavioural brain research, 2005)
Keywords: Acoustic Stimulation; Acoustic Stimulation - methods; Adult and adolescent clinical studies; Animals; Antipsychotic Agents; Antipsychotic Agents - administration & dosage; Behavioral psychophysiology; Biological and medical sciences; Body Temperature; Body Temperature - drug effects; Body Temperature - genetics; Body Weight; Body Weight - drug effects; Body Weight - genetics; Clozapine; Clozapine - administration & dosage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Enzyme Inhibitors; Enzyme Inhibitors - pharmacology; Fundamental and applied biological sciences. Psychology; Gait Disorders, Neurologic; Gait Disorders, Neurologic - drug therapy; Gait Disorders, Neurologic - genetics; Gait Disorders, Neurologic - physiopathology; Hyperlocomotion; Life Sciences; Medical sciences; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Microtubule-Associated Proteins - deficiency; Motor Activity; Motor Activity - drug effects; Motor Activity - genetics; Neural Inhibition; Neural Inhibition - drug effects; Neural Inhibition - genetics; Neuro-developmental disorder; Neurons and Cognition; Neurotransmission and behavior; NMDA NR1 hypomorphic mice; Phencyclidine; Phencyclidine - pharmacology; PPI; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Psychopathology. Psychiatry; Psychoses; Receptors, N-Methyl-D-Aspartate; Receptors, N-Methyl-D-Aspartate - deficiency; Reflex, Acoustic; Reflex, Acoustic - drug effects; Reflex, Acoustic - genetics; Rotarod Performance Test; Rotarod Performance Test - methods; Schizophrenia; Sensorimotor-gating; Somatosensory Cortex; Somatosensory Cortex - drug effects; Somatosensory Cortex - physiopathology; STOP KO mice; Swimming; Time Factors; Neuro-developmental disorder; STOP KO mice; Schizophrenia; PPI; NMDA NR1 hypomorphic mice; Sensorimotor-gating; Hyperlocomotion; Animal model; Targeting; Rodentia; Developmental disorder; Psychosis; Vertebrata; Mammalia; Gene; Mouse; Animal; NMDA; Mutation; Gating