Oral colonization by gram-negative bacilli in patients with hematologic malignancies and solid tumors compared with healthy controls

• Published in: BMC oral health Vol. 23; no. 1; pp. 465 - 8
• Main Authors: Santibañez-Bedolla, Karla E., Orozco-Uriarte, Maria J., Alvarez-Canales, Jose A., Macias, Alejandro E., Amador-Medina, Lauro F.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 08.07.2023; BioMed Central; BMC
• Subjects: Analysis; Anti-Bacterial Agents - therapeutic use; Antibiotics; Bacteria; Blood cancer; Cancer; Care and treatment; Cephalosporins; Colonization; Comorbidity; Composition; Dental hygiene; Diagnosis; Disease susceptibility; E coli; Gram-negative bacilli; Gram-Negative Bacteria; Gram-Negative Bacterial Infections - complications; Gram-Negative Bacterial Infections - drug therapy; Gram-Negative Bacterial Infections - epidemiology; Hematologic Neoplasms - complications; Humans; Hygiene; Infections; Malignancy; Microbiota; Microbiota (Symbiotic organisms); Mouth; Neoplasms - complications; Neoplasms - drug therapy; Oncology; Oral cavity; Oral colonization; Oral health; Oropharynx; Regression analysis; Risk groups; Solid tumors; Tumors; Mexico; Gram-negative bacilli; Oral colonization; Mouth

Colonization of the oropharynx with gram-negative bacilli (GNB) is considered a negative prognostic factor in immunocompromised individuals. Hemato-oncologic patients represent a high-risk group due to their immunodeficiencies and associated treatments. This study aimed to determine the rates of ora...