A Discovery of Relevant Hepatoprotective Effects and Underlying Mechanisms of Dietary Clostridium butyricum Against Corticosterone-Induced Liver Injury in Pekin Ducks

• Published in: Microorganisms (Basel) Vol. 7; no. 9; p. 358
• Main Authors: Liu, Yanhan, Liu, Cun, Huang, Liqing, Xia, Zhaofei
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 16.09.2019; MDPI
• Subjects: 1-Phosphatidylinositol 3-kinase; adipokines; AKT protein; antioxidant activity; Antioxidants; Aquatic birds; Bioengineering; Chlortetracycline; Clostridium butyricum; Corticosterone; Cytokines; Diet; duck feeding; ducks; Ethics; Fatty liver; gene expression regulation; Genes; hepatoprotective effect; hexachlorobenzene; Homeostasis; Immune system; immunomodulation; Immunoregulation; Inflammation; Injuries; Interleukin 1; Interleukin 10; Lipid metabolism; Lipids; Liver; liver function; Metabolism; Necrosis; Oxidative stress; Pekin; Pekin ducks; peroxisome proliferator-activated receptor gamma; Peroxisome proliferator-activated receptors; Physiology; Probiotics; Receptors; RNA-seq; sequence analysis; Signal transduction; Signaling; Steatosis; Toll-like receptors; Tumor necrosis factor-TNF; Waterfowl; Wildfowl; Beijing China; United States > US; China

Clostridium butyricum (C. butyricum) can attenuate oxidative stress, inflammation, and hepatic fatty deposition in poultry, however, the underlying mechanisms for this in Pekin ducks remain unclear. This study evaluated these hepatoprotective effects and the underlying mechanisms in a corticosterone...