Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms - Tortorici, M. Alejandra; Beltramello, Martina; Lempp, Florian A.; Pinto, Dora; Dang, Ha V.; Rosen, Laura E.; McCallum, Matthew; Bowen, John; Minola, Andrea; Jaconi, Stefano; Zatta, Fabrizia; De Marco, Anna; et al. (Science (American Association for the Advancement of Science), 2020)
Keywords: ACE2; Amino Acid Motifs - immunology; Angiotensin-Converting Enzyme 2; Animals; Antibodies; Antibodies, Neutralizing - administration & dosage; Antibodies, Neutralizing - immunology; Antibodies, Neutralizing - isolation & purification; Antibodies, Viral - administration & dosage; Antibodies, Viral - immunology; Antibodies, Viral - isolation & purification; Betacoronavirus - immunology; Biochem; CHO Cells; Coronaviridae; Coronavirus Infections - prevention & control; Coronavirus Infections - therapy; Coronaviruses; COVID-19; Cricetinae; Cricetulus; Cryoelectron Microscopy; Electron microscopy; Epitopes; HEK293 Cells; Humans; Immunodominant Epitopes - chemistry; Immunodominant Epitopes - immunology; Immunology; Microscopy; Microscopy, Electron; Pandemics - prevention & control; Peptidyl-Dipeptidase A - immunology; Pneumonia, Viral - prevention & control; Pneumonia, Viral - therapy; Prophylaxis; Protein Domains - immunology; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus - antagonists & inhibitors; Spike Glycoprotein, Coronavirus - chemistry; Spike Glycoprotein, Coronavirus - immunology; Viral infections