Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells - Ghosh, Chaitali; Hossain, Mohammed; Solanki, Jesal; Najm, Imad M.; Marchi, Nicola; Janigro, Damir (Epilepsia (Copenhagen), 2017)
Keywords: Analysis of Variance; Brain - pathology; Cells, Cultured; Cytochrome P-450 Enzyme System - metabolism; Drug resistance; Drug Resistant Epilepsy - pathology; Endothelial Cells - drug effects; Endothelial Cells - metabolism; Epilepsy; Full‐Length Original Research; Gene Expression Regulation, Enzymologic - drug effects; Gene Expression Regulation, Enzymologic - physiology; Glial Fibrillary Acidic Protein - metabolism; Humans; Life Sciences; Neurovascular unit; Nuclear Receptors; Oligonucleotide Array Sequence Analysis; Phosphopyruvate Hydratase - metabolism; Proliferating Cell Nuclear Antigen - metabolism; Receptors, Glucocorticoid - genetics; Receptors, Glucocorticoid - metabolism; Receptors, Steroid - genetics; Receptors, Steroid - metabolism; RNA, Messenger - metabolism; RNA, Small Interfering - pharmacology; Subcellular Fractions - metabolism; Neurovascular unit; Drug resistance; Epilepsy; Nuclear Receptors