Signatures of Archaic Adaptive Introgression in Present-Day Human Populations

• Published in: Molecular biology and evolution Vol. 34; no. 2; pp. 296 - 317
• Main Authors: Racimo, Fernando, Marnetto, Davide, Huerta-Sánchez, Emilia
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.02.2017
• Subjects: Adaptation, Biological - genetics; Alleles; Animals; Biological Evolution; Computer Simulation; Databases, Nucleic Acid; Discoveries; DNA, Ancient - analysis; Evolution, Molecular; Gene Frequency; Genetics, Population; Haplotypes; Humans; Neanderthals; Phylogeny; Selection, Genetic; Sequence Analysis, DNA - methods; ancient DNA; adaptive introgression; denisova; neanderthal

Comparisons of DNA from archaic and modern humans show that these groups interbred, and in some cases received an evolutionary advantage from doing so. This process—adaptive introgression—may lead to a faster rate of adaptation than is predicted from models with mutation and selection alone. Within...