Timing of First Respiratory Virus Detections in Infants: A Community-Based Birth Cohort Study

• Published in: The Journal of Infectious Diseases Vol. 217; no. 3; pp. 418 - 427
• Main Authors: Sarna, Mohinder, Ware, Robert S, Lambert, Stephen B, Sloots, Theo P, Nissen, Michael D, Grimwood, Keith
• Format: Journal Article Web Resource
• Language: English
• Published: US Oxford University Press 17.01.2018
• Subjects: Age Factors; Cohort Studies; Community-Acquired Infections - epidemiology; Community-Acquired Infections - pathology; Community-Acquired Infections - virology; Editor's Choice; Female; Humans; Infant; Infant, Newborn; Major and Brief Reports; Male; Nasal Cavity - virology; Polymerase Chain Reaction; Pregnancy; Prevalence; Respiratory Tract Infections - epidemiology; Respiratory Tract Infections - pathology; Respiratory Tract Infections - virology; Risk Factors; Virus Diseases - epidemiology; Virus Diseases - pathology; Virus Diseases - virology; Viruses - classification; Viruses - isolation & purification; human rhinovirus; cohort study; primary infection; respiratory viruses; infant; human metapneumovirus; respiratory syncytial virus

Abstract Background Determining timing of first virus detection episodes (fVDEs) for different respiratory viruses in infants identifies risk periods and informs preventive interventions, including vaccination. We describe the ages and nature of fVDEs in an infant birth cohort and explore factors as...