Induction of FoxP3 Pre-mRNA Alternative Splicing to Enhance the Suppressive Activity of Regulatory T Cells from Amyotrophic Lateral Sclerosis Patients - Zhdanov, Dmitry D.; Gladilina, Yulia A.; Blinova, Varvara G.; Abramova, Anna A.; Shishparenok, Anastasia N.; Eliseeva, Daria D. (Biomedicines, 2024)
Keywords: Alternative splicing; Amyotrophic lateral sclerosis; Antibodies; Apoptosis; Autoimmune diseases; CD25 antigen; CD4 antigen; Cell therapy; CTLA-4 protein; Development and progression; Disease; Endopeptidases; Ethylenediaminetetraacetic acid; Exons; Flow cytometry; Forkhead protein; FoxP3; Foxp3 protein; Gene expression; Immunoregulation; Lymphocytes; Lymphocytes T; Medical prognosis; Messenger RNA; Oligonucleotides; Perforin; Peripheral blood; Proteins; regulatory T cells; Serine proteinase; splicing-switching oligonucleotides; suppressive activity; T cells; Telomerase; Transcription factors; Germany; Russia; United States--US; regulatory T cells; splicing-switching oligonucleotides; alternative splicing; FoxP3; amyotrophic lateral sclerosis; suppressive activity