Role of glycoprotein 78 and cidec in hepatic steatosis

• Published in: Molecular medicine reports Vol. 16; no. 2; pp. 1871 - 1877
• Main Authors: Li, Jie, Liu, Guocai, Zhang, Feng, Zhang, Zhiwen, Xu, Yuqiao, Li, Qing
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.08.2017; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: Adipocytes; Animals; Apoptosis; Bioengineering; Care and treatment; Cell culture; Cell death; cell death-inducing DFFA-like effector c; Cell Line; Cholesterol; Energy metabolism; Enzymes; Fatty liver; Fatty Liver - metabolism; Fatty Liver - pathology; Gene Knockdown Techniques; Genetic aspects; glycoprotein 78; Glycoproteins; hepatic cell; Hepatocytes - metabolism; Homeostasis; Immunofluorescence; Lipid metabolism; Lipids; Liver cancer; Liver diseases; Metabolic disorders; Metabolic syndrome; Mice; Microscopy; Physiological aspects; Plasmids; Polymerase chain reaction; Proteins; Proteins - metabolism; Receptors, Autocrine Motility Factor - metabolism; Rodents; Steatosis; Ubiquitin; Ubiquitin-protein ligase; Beijing China; United States > US; China

Hepatic glycoprotein (gp78), a membrane-anchored E3 ubiquitin ligase, has been reported to be involved in regulating lipid and energy metabolism in animals, and cell death-inducing DFFA-like effector c (cidec) has emerged as an important regulator of metabolism, which has been implicated in the proc...