The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects

• Published in: Gastroenterology (New York, N.Y. 1943) Vol. 133; no. 1; p. 24
• Main Authors: Kassinen, Anna, Krogius-Kurikka, Lotta, Mäkivuokko, Harri, Rinttilä, Teemu, Paulin, Lars, Corander, Jukka, Malinen, Erja, Apajalahti, Juha, Palva, Airi
• Format: Journal Article
• Language: English
• Published: United States 01.07.2007
• Subjects: Adult; Aged; Bacteria - genetics; Bacteria - isolation & purification; Base Composition; Bayes Theorem; Cloning, Molecular; DNA, Bacterial - genetics; Feces - microbiology; Female; Gene Library; Humans; Irritable Bowel Syndrome - microbiology; Male; Middle Aged; Phylogeny; RNA, Ribosomal, 16S - genetics

Irritable bowel syndrome (IBS) is a significant gastrointestinal disorder with unknown etiology. The symptoms can greatly weaken patients' quality of life and account for notable economical costs for society. Contribution of the gastrointestinal microbiota in IBS has been suggested. Our objecti...