Evaluation of Immune Modulation by β-1,3; 1,6 D-Glucan Derived from Ganoderma lucidum in Healthy Adult Volunteers, A Randomized Controlled Trial

• Published in: Foods Vol. 12; no. 3; p. 659
• Main Authors: Chen, Shiu-Nan, Nan, Fan-Hua, Liu, Ming-Wei, Yang, Min-Feng, Chang, Ya-Chih, Chen, Sherwin
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 03.02.2023; MDPI
• Subjects: adults; Biocompatibility; Blood; blood serum; CD3 antigen; CD4 antigen; CD8 antigen; Chronic fatigue syndrome; Clinical trials; Cytotoxicity; Disease; Food science; Fungi; Ganoderma lucidum; Glucan; Hematology; humans; immune modulation; Immune response; Immune system; Immunoglobulin A; Immunomodulation; In vivo methods and tests; Informed consent; innate and adaptive immune response; Intervention; kidneys; liver function; Lymphocytes; Lymphocytes T; Mushrooms; Natural killer cells; NMR; Nuclear magnetic resonance; Placebos; randomized clinical trials; Reishi; Spectrum analysis; Statistical analysis; T-lymphocytes; Toxicity; β-Glucan; United States > US; Taiwan; Creatinine; Reishi; β-glucan; innate and adaptive immune response; Ganoderma lucidum; T-lymphocytes; immune modulation; randomized control trials

Fungi-derived β-glucan, a type of glucopolysaccharide, has been shown to possess immune-modulatory properties in clinical settings. Studies have indicated that β-glucan derived from Ganoderma lucidum (commonly known as Reishi) holds particular promise in this regard, both in laboratory and in vivo s...