PAR-4/Ca2+-calpain pathway activation stimulates platelet-derived microparticles in hyperglycemic type 2 diabetes - Giannella, Alessandra; Ceolotto, Giulio; Radu, Claudia Maria; Cattelan, Arianna; Iori, Elisabetta; Benetti, Andrea; Fabris, Fabrizio; Simioni, Paolo; Avogaro, Angelo; Vigili de Kreutzenberg, Saula (Cardiovascular diabetology, 2021)
Keywords: Angiology; Binding sites; Blood platelets; Calcium; Calpain; Cardiology; CD45 antigen; Cholesterol; Chromatography; Cytokines; Diabetes; Diabetes mellitus (non-insulin dependent); Extracellular vesicles; Flow cytometry; Glucose; Glucose tolerance; Glycated hemoglobin; Hemoglobin; Hyperglycemia; Inflammation; Intercellular adhesion molecule 1; Interleukin 6; Macrophages; Medicine; Medicine & Public Health; Metabolism; Microparticles; NF-kB; NF-κB protein; Original Investigation; Plasma; Plasma levels; Platelet activation; Platelets; Proteinase-activated receptor 1; THP-1 transformed macrophages; Thrombin; Tissue factor; Vascular cell adhesion molecule 1; Italy; Austria; Netherlands; Miami Florida; United States--US; Europe; Extracellular vesicles; NF; B; Platelet activation; THP-1 transformed macrophages; Glycated hemoglobin