Clonal expansions in ulcerative colitis identify patients with neoplasia - Salk, Jesse J; Salipante, Stephen J; Risques, Rosa Ana; Crispin, David A; Li, Lin; Bronner, Mary P; Brentnall, Teresa A; Rabinovitch, Peter S; Horwitz, Marshall S; Loeb, Lawrence A (Proceedings of the National Academy of Sciences - PNAS, 2009)
Keywords: Alleles; Biological Sciences; Biopsies; Biopsy; Cancer; Carcinogenesis; Cell lines; Cell Proliferation; Clone Cells; clones; Cloning; colitis; Colitis, Ulcerative - pathology; colon; Colonic Neoplasms - diagnosis; Colonic Neoplasms - pathology; colorectal neoplasms; Electrophoresis, Agar Gel; evolution; Genetic mutation; Genotype; Genotypes; Guanine - metabolism; Histology; Humans; inflammation; Inflammatory bowel disease; Models, Biological; mutants; Mutation; Mutation - genetics; patients; risk; Risk factors; Stem cells; Tissues; Tumors; Ulcerative colitis