Association of atrial fibrillation and amino-terminal pro–brain natriuretic peptide concentrations in dyspneic subjects with and without acute heart failure: Results from the ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) study

• Published in: The American heart journal Vol. 153; no. 1; pp. 90 - 97
• Main Authors: Morello, Angela, Lloyd-Jones, Donald M., Chae, Claudia U., van Kimmenade, Roland R.J., Chen, Annabel C., Baggish, Aaron L., O'Donoghue, Michelle, Lee-Lewandrowski, Elizabeth, Januzzi, James L.
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 2007; Elsevier; Elsevier Limited
• Subjects: Acute coronary syndromes; Age; Aged; Aged, 80 and over; Atrial Fibrillation - blood; Atrial Fibrillation - complications; Biological and medical sciences; Blood pressure; Cardiac dysrhythmias; Cardiology. Vascular system; Cardiomyopathy; Cardiovascular; Cardiovascular disease; Dyspnea - blood; Dyspnea - etiology; Family medical history; Female; Heart; Heart attacks; Heart failure; Heart Failure - complications; Heart Failure - diagnosis; Heart failure, cardiogenic pulmonary edema, cardiac enlargement; Humans; Linear Models; Logistic Models; Male; Medical sciences; Middle Aged; Natriuretic Peptide, Brain - blood; Peptide Fragments - blood; Peptides; Pneumology; Respiratory system : syndromes and miscellaneous diseases; Risk Factors; Software; Human; Heart failure; Brain natriuretic peptide; Arrhythmia; Respiratory disease; Acute; Atrial fibrillation; Cardiovascular disease; Concentration; Phlebology; Excitability disorder; Result; Association; Dyspnea; Emergency department; Heart disease; Circulatory system; Cardiology; Aminoacid sequence

Amino-terminal pro–brain natriuretic peptide (NT-proBNP) testing is useful for diagnosis or exclusion of heart failure (HF) in dyspneic patients. Atrial fibrillation (AF) may cause dyspnea in the absence of acute HF and may also affect plasma levels of NT-proBNP. We prospectively enrolled 599 patien...