Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability - Milazzo, Giorgio; Mercatelli, Daniele; Di Muzio, Giulia; Triboli, Luca; De Rosa, Piergiuseppe; Perini, Giovanni; Giorgi, Federico M. (Genes, 2020)
Keywords: antineoplastic agents; Antineoplastic Agents - therapeutic use; Arthropods; Cell cycle; Chelonia mydas; chromatin; Chromatin remodeling; Enzymes; Eukaryotes; Evolutionary conservation; Gene expression; Genomes; HDAC protein; Histone deacetylase; Histone Deacetylase Inhibitors - therapeutic use; Histone Deacetylases - genetics; Histones; Histones - genetics; Humans; Insects; Mammals; moieties; Nematodes; Neoplasms - genetics; Neoplasms - therapy; Organisms; Pathogenesis; Phylogenetics; Proteins; Reptiles & amphibians; Review; Substrate Specificity - genetics; tissues; Transcription; transcription (genetics); Transcription Factors - genetics; Yeast; Zebrafish; gene networks; phylogenesis; epigenomics; histone deacetylases; HDAC inhibitors; cancer; chromatin; HDACi; epigenetics; HDAC