Alveolar Type 2 Epithelial Cell Organoids: Focus on Culture Methods

• Published in: Biomedicines Vol. 11; no. 11; p. 3034
• Main Authors: Jain, Krishan Gopal, Xi, Nan Miles, Zhao, Runzhen, Ahmad, Waqas, Ali, Gibran, Ji, Hong-Long
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.11.2023
• Subjects: 3D cultures; alveolar type 2 cells; Alveoli; Analysis; Cell culture; Cell therapy; Drug screening; Embryo cells; Embryonic stem cells; Epithelial cells; Growth factors; Health aspects; Immunomodulation; Laboratories; Lung diseases; Lungs; Medical research; Medical screening; Medicine, Experimental; Methods; Organoids; Physiology; Pluripotency; Progenitor cells; pulmonary diseases; Respiratory diseases; Stem cells; pulmonary diseases; stem cells; alveolar type 2 cells; 3D cultures; organoids

Lung diseases rank third in terms of mortality and represent a significant economic burden globally. Scientists have been conducting research to better understand respiratory diseases and find treatments for them. An ideal in vitro model must mimic the in vivo organ structure, physiology, and pathol...