Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation
Dendritic cells (DCs) promote either tolerogenic or immunogenic T cell responses, the latter upon sensing microbes. Using an in vitro system, we analyzed transcriptional determinants that enable mature DCs to direct these opposing T cell outcomes. In the absence of microbial products, the transcript...
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Published in | The Journal of cell biology Vol. 216; no. 3; pp. 779 - 792 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Rockefeller University Press
06.03.2017
The Rockefeller University Press |
Subjects | |
Online Access | Get full text |
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