Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation

Dendritic cells (DCs) promote either tolerogenic or immunogenic T cell responses, the latter upon sensing microbes. Using an in vitro system, we analyzed transcriptional determinants that enable mature DCs to direct these opposing T cell outcomes. In the absence of microbial products, the transcript...

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Bibliographic Details
Published inThe Journal of cell biology Vol. 216; no. 3; pp. 779 - 792
Main Authors Vander Lugt, Bryan, Riddell, Jeremy, Khan, Aly A, Hackney, Jason A, Lesch, Justin, DeVoss, Jason, Weirauch, Matthew T, Singh, Harinder, Mellman, Ira
Format Journal Article
LanguageEnglish
Published United States Rockefeller University Press 06.03.2017
The Rockefeller University Press
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