Prediction of antiviral efficacy in patients with chronic hepatitis C by changes in forkhead box protein 3 levels

• Published in: Experimental and therapeutic medicine Vol. 8; no. 1; pp. 165 - 168
• Main Authors: CHANG, JIA-BAO, XUE, RONG, ZHOU, ZHEN-XIAN, FENG, YAN-HONG, DAI, WEI-WEI, QIU, JIE, YANG, YONG-FENG
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.07.2014; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: Antiviral agents; Antiviral drugs; CD4+CD25+ forkhead box P3+ regulatory T cells; chronic hepatitis C; Dosage and administration; Drug therapy; Health aspects; Hepatitis C; hepatitis C virus-RNA load; Interferon; Liver; Patient outcomes; Studies; T cells; Transcription factors; Viral infections; China; hepatitis C virus-RNA load; CD4+CD25+ forkhead box P3+ regulatory T cells; chronic hepatitis C

The aim of the present study was to investigate the distribution of CD4+CD25+ regulatory T cells (Tregs) in the peripheral blood of patients with chronic hepatitis C; in addition to identifying whether the distribution of CD4+CD25+ Tregs predicts the efficacy of antiviral therapy for HCV. The expres...