Prediction of imminent, severe deterioration of children with parallel circulations using real-time processing of physiologic data

• Published in: The Journal of thoracic and cardiovascular surgery Vol. 152; no. 1; pp. 171 - 177
• Main Authors: Rusin, Craig G., PhD, Acosta, Sebastian I., PhD, Shekerdemian, Lara S., MD, Vu, Eric L., MD, Bavare, Aarti C., MD, MPH, Myers, Risa B., MS, Patterson, Lance W., BS, Brady, Ken M., MD, Penny, Daniel J., MD, PhD, MHA
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2016
• Subjects: Algorithms; Cardiopulmonary Resuscitation; Cardiothoracic Surgery; Child; Child, Preschool; critical deterioration; Female; Follow-Up Studies; Hospitalization - trends; Humans; Hypoplastic Left Heart Syndrome - diagnosis; Hypoplastic Left Heart Syndrome - physiopathology; Hypoplastic Left Heart Syndrome - surgery; Infant; Intensive Care Units, Pediatric; Male; Monitoring, Physiologic - methods; predictive analytics; Prospective Studies; Pulmonary Circulation - physiology; ROC Curve; single ventricle; Texas; Time Factors; SpO 2; CPR; hypoplastic left heart syndrome; single ventricle; institutional review board; cardiovascular intensive care unit; cardiopulmonary resuscitation; electrocardiogram; extracorporeal membrane oxygenation; intensive care unit; receiver operating characteristic; ECMO; Texas Children's Hospital; peripheral capillary oxygen saturation; predictive analytics; ROC; ECG; BCM; HLHS; CVICU; critical deterioration; IRB; TCH; Baylor College of Medicine; ICU; SpO2

Abstract Objectives Sudden death is common in patients with hypoplastic left heart syndrome and comparable lesions with parallel systemic and pulmonary circulation from a common ventricular chamber. It is hypothesized that unforeseen acute deterioration is preceded by subtle changes in physiologic d...