Luteinizing Hormone Facilitates Antral Follicular Maturation and Survival via Thecal Paracrine Signaling in Cattle

• Published in: Endocrinology (Philadelphia) Vol. 159; no. 6; pp. 2337 - 2347
• Main Authors: Hattori, Katsushige, Orisaka, Makoto, Fukuda, Shin, Tajima, Kimihisa, Yamazaki, Yukiko, Mizutani, Tetsuya, Yoshida, Yoshio
• Format: Journal Article
• Language: English
• Published: Washington, DC Endocrine Society 01.06.2018; Oxford University Press
• Subjects: Androgens; Animals; Apoptosis; Aromatase; Biosynthesis; Cattle; Cell Survival - drug effects; Cells, Cultured; Collagen; Dependence; Endocrinology; Estrogens; Female; Follicle Stimulating Hormone - pharmacology; Follicle-stimulating hormone; Follicles; Follicular Phase - drug effects; Gonadotropins; Granulosa cells; Granulosa Cells - drug effects; Granulosa Cells - metabolism; In Vitro Oocyte Maturation Techniques; Insulin-like growth factor I; Luteinizing hormone; Luteinizing Hormone - pharmacology; Maturation; Menopause; Menstrual cycle; Oogenesis - drug effects; Oogenesis - physiology; Ovarian Follicle - drug effects; Ovarian Follicle - physiology; Paracrine Communication - drug effects; Paracrine signalling; Pituitary (anterior); Pregnancy; Reproductive technologies; Sensitivity; Stimulation; Substrates; Supplements; Survival; Theca; Theca Cells - drug effects; Theca Cells - metabolism

Abstract LH supplementation in assisted reproductive technology cycles improves the ongoing pregnancy rate in women with poor ovarian response (POR). However, our knowledge of the precise role of LH during the follicular phase of the menstrual cycle is incomplete. To explore the role of LH in the ma...