genetically modulated, intrinsic cingulate circuit supports human nicotine addiction - Hong, L. Elliot; Hodgkinson, Colin A; Yang, Yihong; Sampath, Hemalatha; Ross, Thomas J; Buchholz, Brittany; Salmeron, Betty Jo; Srivastava, Vibhuti; Thaker, Gunvant K; Goldman, David; Stein, Elliot A (Proceedings of the National Academy of Sciences - PNAS, 2010)
Keywords: 3' Untranslated Regions - genetics; Acetylcholine receptors (nicotinic); Addiction; Addictions; Adolescent; Adult; Alleles; Amygdala; Amygdala - anatomy & histology; Amygdala - physiology; Basal Ganglia - anatomy & histology; Basal Ganglia - physiology; Biological Sciences; biomarkers; Brain; Brain Mapping; cholinergic receptors; Cigarette smoking; Circuits; Connectivity; Female; Gene expression; Gene Frequency; Genomics; Genotype; Genotypes; Gyrus Cinguli - anatomy & histology; Gyrus Cinguli - physiology; Human genetics; Humans; Linkage Disequilibrium; Magnetic Resonance Imaging; Male; Medical genetics; Mental disorders; Middle Aged; Neostriatum; Nerve Tissue Proteins - genetics; Neural conduction; Neural networks; Neural Pathways - anatomy & histology; Neural Pathways - metabolism; Neural Pathways - physiology; Nicotine; Polymorphism, Single Nucleotide; Proteins; Receptors, Nicotinic - genetics; risk; Risk factors; Risk groups; Risk taking; Smoking; Smoking - genetics; Smoking - physiopathology; Smoking - psychology; Smoking cessation; Tobacco smoking; Tobacco Use Disorder - genetics; Tobacco Use Disorder - physiopathology; Tobacco Use Disorder - psychology; Young Adult