Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach - Chen, Lian; Cui, Hengmin (International journal of molecular sciences, 2015)
Keywords: Amino acids; Animals; Apoptosis; Apoptosis - drug effects; Cancer therapies; Enzyme Inhibitors - pharmacology; Enzyme Inhibitors - therapeutic use; Gene Expression Regulation, Neoplastic; Glutaminase - antagonists & inhibitors; Glutaminase - genetics; Glutaminase - metabolism; Glutamine - metabolism; Humans; Hypoxia-Inducible Factor 1 - genetics; Hypoxia-Inducible Factor 1 - metabolism; Metabolism; Neoplasms - genetics; Neoplasms - metabolism; Neoplasms - pathology; Neoplasms - therapy; Proto-Oncogene Proteins c-myc - genetics; Proto-Oncogene Proteins c-myc - metabolism; ras Proteins - genetics; ras Proteins - metabolism; Review; Tumor Suppressor Protein p53 - genetics; Tumor Suppressor Protein p53 - metabolism; glutamine metabolism; glutaminase; apoptosis; cancer