Advanced Lipid Technologies® (ALT®): A Proven Formulation Platform to Enhance the Bioavailability of Lipophilic Compounds

• Published in: Journal of drug delivery Vol. 2019; pp. 1957360 - 10
• Main Authors: Lopez-Toledano, Miguel A., Saxena, Vaibhav, Legassie, Jason D., Liu, Haiyang, Ghanta, Ajay, Riseman, Stephen, Cocilova, Courtney, Daak, Ahmed, Thorsteinsson, Thorsteinn, Rabinowicz, Adrian L., Sancilio, Frederick D.
• Format: Journal Article
• Language: English
• Published: Egypt Hindawi 31.07.2019; John Wiley & Sons, Inc
• Subjects: Clathrate compounds; Cyclodextrins; Drug delivery systems; Drugs; Fatty acids; Health aspects; Review; Surface active agents; Vehicles

Despite recent advances, the drug development process continues to face significant challenges to efficiently improve the poor solubility of active pharmaceutical ingredients (API) in aqueous media or to improve the bioavailability of lipid-based formulations. The inherent high intra- and interindiv...