Vitamin D Endocrine System and COVID‐19

• Published in: JBMR plus Vol. 5; no. 12; pp. e10576 - n/a
• Main Authors: Bouillon, Roger, Quesada‐Gomez, José Manuel
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.12.2021; Oxford University Press
• Subjects: 25-Hydroxyvitamin D; ACUTE RESPIRATORY DISTRESS SYNDROME; CALCIFEDIOL; Clinical trials; Coronaviruses; COVID-19; Dietary supplements; Endocrine system; Health care; Inflammation; INTENSIVE CARE TREATMENT; Lymphocytes; MORTALITY; Original; Respiratory distress syndrome; Tumor necrosis factor-TNF; VITAMIN D; MORTALITY; CALCIFEDIOL; ACUTE RESPIRATORY DISTRESS SYNDROME; COVID‐19; INTENSIVE CARE TREATMENT; VITAMIN D

ABSTRACT Preclinical data strongly suggest that the vitamin D endocrine system (VDES) may have extraskeletal effects. Cells of the immune and cardiovascular systems and lungs can express the vitamin D receptor, and overall these cells respond in a coherent fashion when exposed to 1,25‐dihydroxyvitam...