Calcium Channel Alterations in Genetic Hypertension

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 14; no. 4; pp. 453 - 456
• Main Authors: Hermsmeyer, Kent, Rusch, Nancy J
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA American Heart Association, Inc 01.10.1989; Hagerstown, MD Lippincott
• Subjects: Animals; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Calcium - physiology; Calcium Channels - physiology; Cardiology. Vascular system; Cells, Cultured; Egtazic Acid - pharmacology; Experimental diseases; Hypertension - genetics; Hypertension - physiopathology; In Vitro Techniques; Medical sciences; Muscle, Smooth, Vascular - physiopathology; Rats; Rats, Inbred SHR - physiology; Rats, Inbred Strains - physiology; Rats, Inbred WKY; Hypertension; Cell culture; Calcium; Rat; Rodentia; Ion transport; Cardiovascular disease; Smooth muscle; Ionic channel; Hereditary; Vertebrata; Mammalia; Membrane transport; Animal; Blood vessel; Cell

We proposed earlier that voltage-dependent calcium (Ca) current is altered in single azygos venous cells from Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR). In this study, the effects of different intracellular concentrations of ethylene glycol-bis- N,N,Nʼ,NʼVtetraacetic acid (EG...