Advanced Maternal Age‐associated SIRT1 Deficiency Compromises Trophoblast Epithelial−Mesenchymal Transition through an Increase in Vimentin Acetylation - Xiong, Liling; Ye, Xuan; Chen, Zhi; Fu, Huijia; Li, Sisi; Xu, Ping; Yu, Jiaxiao; Wen, Li; Gao, Rufei; Fu, Yong; Qi, Hongbo; Kilby, Mark D.; et al. (Aging cell, 2021)
Keywords: Acetylation; Achievement tests; advanced maternal age; Age; Aged; Animals; Biomarkers; Cell cycle; Cross-breeding; Embryos; Epithelial-Mesenchymal Transition - immunology; epithelial−mesenchymal transition; Female; Fetuses; Humans; Invasiveness; Life cycles; Mass spectroscopy; Maternal Age; Mesenchyme; Mice; NAD; Original Paper; Original Papers; p53 Protein; Placenta; Pregnancy; Protein expression; Proteins; Senescence; SIRT1; SIRT1 protein; Sirtuin 1 - metabolism; Therapeutic targets; trophoblast; Trophoblasts; Trophoblasts - metabolism; Vimentin; Vimentin - adverse effects; Wound healing; senescence; epithelial−mesenchymal transition; placenta; trophoblast; SIRT1; advanced maternal age