Abnormal brain activation and connectivity to standardized disorder-related visual scenes in social anxiety disorder

• Published in: Human brain mapping Vol. 37; no. 4; pp. 1559 - 1572
• Main Authors: Heitmann, Carina Yvonne, Feldker, Katharina, Neumeister, Paula, Zepp, Britta Maria, Peterburs, Jutta, Zwitserlood, Pienie, Straube, Thomas
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.04.2016; John Wiley & Sons, Inc; John Wiley and Sons Inc
• Subjects: Adult; amygdala; Anxiety Disorders - diagnostic imaging; Anxiety Disorders - physiopathology; default-mode-network; Female; globus pallidus; Humans; Magnetic Resonance Imaging - methods; Male; Nerve Net - diagnostic imaging; Nerve Net - physiopathology; Phobia, Social - diagnostic imaging; Phobia, Social - physiopathology; Photic Stimulation - methods; Pilot Projects; precuneus; psychophysiological interaction; Random Allocation; self-referential processing; social phobia; Young Adult; amygdala; default-mode-network; precuneus; social phobia; self-referential processing; psychophysiological interaction; globus pallidus

Our understanding of altered emotional processing in social anxiety disorder (SAD) is hampered by a heterogeneity of findings, which is probably due to the vastly different methods and materials used so far. This is why the present functional magnetic resonance imaging (fMRI) study investigated imme...